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Two-carbon nitrogen ring bases (adenine and guanine) covalently linked to a sugar (ribose or deoxyribose) and one to three phosphate groups; can function as extracellular messengers, antimetabolites, and chain terminators that inhibit viral DNA polymerase.
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Adenosine 5'-monophosphate monohydrate is an analytical standard intended for research and analytical applications. It is commonly used in qualitative, quantitative, and methodological research experiments. It is also identified as an endogenous metabolite.
Analytical standard for research applications.
Used in qualitative, quantitative, and methodological research experiments.
Applied in techniques such as HPLC, GC, and MS.
Identified as an endogenous metabolite.
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7-Methyl-guanosine-5'-triphosphate (m7GTP) sodium is a guanosine 5'-phosphate. Its phosphorothioate analog acts as a potent cap-dependent translation inhibitor.
Is a guanosine 5'-phosphate.
Functions as a potent cap-dependent translation inhibitor.
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8-Azido-ATP is a ribonucleoside triphosphate analog with an azido group substitution at the adenine C-8 position It acts primarily as an ATP mimic interacting with poly(A) polymerase (PAP) specifically illustrated using yeast poly(A) polymerase (yPAP) Incorporation of 8-azido-ATP into growing polyadenylation chains results in premature termination and moderately shorter poly(A) tails relative to natural ATP substrates Due to its chain-terminating capacity and altered substrate specificity 8-azido-ATP is applied in biochemical studies examining enzyme fidelity nucleotide selection mechanisms and RNA polymerase activity
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Adenosine 5'-diphosphate dicyclohexylammonium is a nucleoside diphosphate that is the product of ATP dephosphorylation by ATPases. It induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors.
Nucleoside diphosphate.
Product of ATP dephosphorylation by ATPases.
Induces human platelet aggregation.
Inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors.
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GTP-14564 is a tyrosine kinase inhibitor that targets internal tandem duplication (ITD) and FLT3. It inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells.
Tyrosine kinase inhibitor
Targets internal tandem duplication (ITD) and FLT3
Inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells
For research use only
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Adenosine A1 receptor activator T62 is a selective positive allosteric modulator of the adenosine A1 receptor supplied for in vitro research. It is available as a solid or as a ready-to-use 10 mM solution in DMSO, with reported purity of 98.93% and a molecular weight of 291.80 g/mol. Follow the SDS for storage and safe handling.
Allosteric enhancer of adenosine A1 receptor.
Available as solid or 10 mM solution in DMSO.
High reported purity suitable for biochemical and cellular assays.
High solubility in DMSO (100 mg/mL) for easy formulation.
Multilingual SDS provided for safety and handling guidance.
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Adenosine receptor antagonist 2 is an orally active A2a/A2b adenosine receptor antagonist with IC50s of 1 nM and 3 nM, respectively. It has anti-tumor activity.
Orally active A2a/A2b adenosine receptor antagonist
IC50s of 1 nM (A2a) and 3 nM (A2b)
Anti-tumor activity
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